Journal: BMJ Open

Article Title: Rationale and design of BERLIN VT study: a multicenter randomised trial comparing preventive versus deferred ablation of ventricular tachycardia

doi: 10.1136/bmjopen-2018-022910

Figure Lengend Snippet: Inclusion and exclusion criteria

Article Snippet: History of remote myocardial infarction Left ventricular ejection fraction ≥30% to ≤50% as estimated by cardiac MRI, 3D echocardiography or via ventriculography within 30 days before enrollment Documentation of sustained VT by any kind of ECG including 12-lead ECG, Holter ECG, rhythm strip, event monitoring, event recorder or pacemaker within 30 days before enrollment ICD indication for secondary prevention Patients who are planned to be implanted with Biotronik ICDs (single-chamber, dual-chamber, triple-chamber or DX device) Patient has provided written informed consent Patient accepts activation of Home Monitoring , Age <18 years or >80 years Known arterial or venous thrombosis Class IV NYHA heart failure Valvular heart disease or mechanical heart valve precluding access to the left ventricle Acute myocardial reinfarction or acute coronary syndrome Cardiac surgery involving cardiotomy within the past 2 months Patients requiring chronic renal dialysis Thrombocytopenia or coagulopathy Incessant VT or electrical storm Bundle-branch reentry tachycardia as the presenting VT Pre-existing ICD Pregnancy or breast feeding women Acute illness or active systemic infection Other disease process likely to limit survival to <12 months Significant medical problem that in the opinion of the principal investigator would preclude enrollment in the study Unwillingness to participate or lack of availability for follow-up Participation in another interventional clinical investigation during the course of the study (participation in a non-interventional clinical investigation is allowed).

Techniques: Stripping Membranes, Activation Assay, Infection